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Direct trains › From Brussels

Brussels → Prague

Prague → Brussels ⇄
3 a weekfastest 15h29European SleeperNight train

Direct trains · no change

  • 18:06 → 10:54+1
    European Sleeper 453 Night train
    Brussel-Zuid → Praha hlavní nádraží · via Antwerp, Rotterdam, The Hague, Amsterdam
    16h4813 stops
    Runs: Mon, Wed, Fri (some weeks)European Sleeper ↗
  • 18:06 → 11:00+1
    European Sleeper 453 Night train
    Brussel-Zuid → Praha hlavní nádraží · via Antwerp, Rotterdam, The Hague, Amsterdam
    16h5410 stops
    Runs: Only Fri 2 Octopen data confirms only these dates; it may run on othersEuropean Sleeper ↗
  • 19:22 → 11:00+1
    European Sleeper 453 Night train
    Brussel-Zuid → Praha hlavní nádraží · via Antwerp, Rotterdam, The Hague, Amsterdam
    15h3810 stops
    Runs: Only Wed 30 Sepopen data confirms only these dates; it may run on othersEuropean Sleeper ↗
  • 19:22 → 10:51+1
    European Sleeper 453 Night train
    Brussel-Zuid → Praha hlavní nádraží · via Antwerp, Rotterdam, The Hague, Amsterdam
    15h2914 stops
    Runs: Only Mon 28 Sepopen data confirms only these dates; it may run on othersEuropean Sleeper ↗

Local times at each station. From official open timetable data (de_delfi, de_rv, esleeper, nl_ovapi) for 28 Sep – 25 Oct 2026; timetables change, so check with the operator before you travel. How we build this.

Door to door vs flying

Overnight: leave 19:22, arrive 10:51

The plane is -12h44 quicker on paper, but the night train uses your night instead of a day and saves a hotel.

Train · fastest direct15h41
  • To Brussel-Zuid1 min
  • Before departure10 min
  • European Sleeper 45315h29
  • From Praha hlavní nádraží1 min
Plane · nonstop BRU–PRG4h25
  • To Brussels (BRU)20 min
  • Check-in & security1h30
  • Flight BRU–PRG1h40
  • Landing to exit20 min
  • From PRG35 min

From city centre to city centre unless you pick otherwise. Getting to stations and airports: typical public-transport times (estimates). Airport: check-in & security 1h30 before, 20 min to get out after landing. Flight time is typical for the distance. Nonstop airlines: Brussels Airlines, Smartwings.