Lyon → Milan

2.1 a dayfastest 4h36TrenitaliaHigh-speed

Direct trains · no change

06:32 → 11:50
Frecciarossa High-speed
Estación de tren Lyon Part Dieu → Milano Centrale · via Chambéry, Turin
5h187 stops
Runs: Only Mon 12 Oct, Tue 13 Oct, Wed 14 Oct, Thu 15 Oct, Fri 16 Oct…Trenitalia ↗
08:32 → 13:50
FR 9281 High-speed
Estación de tren Lyon Part Dieu → Milano Centrale · via Chambéry, Turin
5h185 stops
Runs: Only Mon 12 Oct, Tue 13 Oct, Wed 14 Oct, Thu 15 Oct, Fri 16 Oct…Trenitalia ↗
09:31 → 14:07
FR 9281 High-speed
Estación de tren Lyon Part Dieu → Milano Centrale · via Chambéry, Turin
4h365 stops
Runs: Sat, Sun (some weeks)Trenitalia ↗
15:23 → 20:07
Frecciarossa High-speed
Estación de tren Lyon Part Dieu → Milano Centrale · via Chambéry, Turin
4h445 stops
Runs: Sat (some weeks)Trenitalia ↗
16:23 → 21:07
Frecciarossa High-speed
Estación de tren Lyon Part Dieu → Milano Centrale · via Chambéry, Turin
4h445 stops
Runs: Only Sun 25 Octopen data confirms only these dates; it may run on othersTrenitalia ↗
17:23 → 22:07
FR 9287 High-speed
Estación de tren Lyon Part Dieu → Milano Centrale · via Chambéry, Turin
4h445 stops
Runs: Sat, Sun (some weeks)Trenitalia ↗

Local times at each station. From official open timetable data (it, trenitalia_fr) for 28 Sep – 25 Oct 2026; timetables change, so check with the operator before you travel. How we build this.

Door to door vs flying

The plane is faster by 29 min

Train · fastest direct4h49

Before departure10 min
FR 92814h36
From Milano Centrale3 min

Plane · nonstop LYS–MXP4h20

To Lyon–Saint-Exupéry (LYS)30 min
Check-in & security1h30
Flight LYS–MXP1h05
Landing to exit20 min
From MXP55 min

From city centre to city centre unless you pick otherwise. Getting to stations and airports: typical public-transport times (estimates). Airport: check-in & security 1h30 before, 20 min to get out after landing. Flight time is typical for the distance. Nonstop airlines: Twin Jet.