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Direct trains › From Karlsruhe

Karlsruhe → Prague

Prague → Karlsruhe ⇄
6 a weekfastest 10h16Deutsche BahnIntercity

Direct trains · no change

  • 23:09 → 09:25+1
    EC 459 Intercity
    Karlsruhe Hbf → Praha hlavní nádraží · via Mannheim, Frankfurt, Leipzig, Dresden
    10h1610 stops
    Runs: Mon–Sat (some weeks)Deutsche Bahn ↗

Local times at each station. From official open timetable data (czptt, de_delfi) for 28 Sep – 25 Oct 2026; timetables change, so check with the operator before you travel. How we build this.

Door to door vs flying

The plane is faster by 4h40
Train · fastest direct10h30
  • To Karlsruhe Hbf3 min
  • Before departure10 min
  • EC 45910h16
  • From Praha hlavní nádraží1 min
Plane · nonstop FRA–PRG5h50
  • To Frankfurt (FRA)2h10
  • Check-in & security1h30
  • Flight FRA–PRG1h15
  • Landing to exit20 min
  • From PRG35 min

From city centre to city centre unless you pick otherwise. Getting to stations and airports: typical public-transport times (estimates). Airport: check-in & security 1h30 before, 20 min to get out after landing. Flight time is typical for the distance. Nonstop airlines: Air Dolomiti, Condor, Lufthansa.