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Direct trains › From Brussels

Brussels → Lugano

Lugano → Brussels ⇄
3 a weekfastest 14h34European SleeperNight train

Direct trains · no change

  • 17:17 → 09:40+1
    European Sleeper 401 Night train
    Brussel-Zuid → Lugano · via Aachen, Cologne, Bellinzona
    16h238 stops
    Runs: Only Mon 28 Sep, Mon 5 Oct, Mon 12 Oct, Mon 19 Octopen data confirms only these dates; it may run on othersEuropean Sleeper ↗
  • 18:17 → 10:18+1
    European Sleeper 401 Night train
    Brussel-Zuid → Lugano · via Aachen, Cologne, Bellinzona
    16h018 stops
    Runs: Only Sat 17 Octopen data confirms only these dates; it may run on othersEuropean Sleeper ↗
  • 18:17 → 09:40+1
    European Sleeper 401 Night train
    Brussel-Zuid → Lugano · via Aachen, Cologne, Bellinzona
    15h238 stops
    Runs: Only Sat 10 Oct, Sat 24 Octopen data confirms only these dates; it may run on othersEuropean Sleeper ↗
  • 18:32 → 09:40+1
    European Sleeper 401 Night train
    Brussel-Zuid → Lugano · via Aachen, Cologne, Bellinzona
    15h088 stops
    Runs: Only Sat 3 Octopen data confirms only these dates; it may run on othersEuropean Sleeper ↗
  • 19:06 → 10:18+1
    European Sleeper 401 Night train
    Brussel-Zuid → Lugano · via Aachen, Cologne, Bellinzona
    15h128 stops
    Runs: Only Thu 15 Oct, Thu 22 Octopen data confirms only these dates; it may run on othersEuropean Sleeper ↗
  • 19:06 → 09:40+1
    European Sleeper 401 Night train
    Brussel-Zuid → Lugano · via Aachen, Cologne, Bellinzona
    14h348 stops
    Runs: Only Thu 1 Oct, Thu 8 Octopen data confirms only these dates; it may run on othersEuropean Sleeper ↗

Local times at each station. From official open timetable data (de_delfi, de_rv, esleeper) for 28 Sep – 25 Oct 2026; timetables change, so check with the operator before you travel. How we build this.

Door to door vs flying

Overnight: leave 19:06, arrive 09:40

The plane is -10h05 quicker on paper, but the night train uses your night instead of a day and saves a hotel.

Train · fastest direct14h45
  • To Brussel-Zuid1 min
  • Before departure10 min
  • European Sleeper 40114h34
Plane · nonstop BRU–MXP4h50
  • To Brussels (BRU)20 min
  • Check-in & security1h30
  • Flight BRU–MXP1h40
  • Landing to exit20 min
  • From MXP1h00

From city centre to city centre unless you pick otherwise. Getting to stations and airports: typical public-transport times (estimates). Airport: check-in & security 1h30 before, 20 min to get out after landing. Flight time is typical for the distance. Nonstop airlines: Brussels Airlines.